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The Human Liver: A Vital Organ in the Body
Human Liver is an important organ of the body which is located in the upper part of the abdomen on the right side. It plays important role in the digestion of the food products in the body through the excretion of bile and other Bio-enzymes, which helps in the digestion of carbohydrates and fats simultaneously. It acts as a storage house for many molecules like glucose and glycogen. It plays important role in the excretion of waste material from the body. During the course of its functioning, it is exposed to wide variety of adverse agents like toxic materials in the form of waste and many infective agents like bacteria, viruses and fungus. Human liver Is exposed to wide variety of diseases like hepatitis,metabolic disorders and complex diseases like liver cancer.
Understanding Liver Cancer Symptoms
Liver Cancer can present in wide variety of symptoms. Depending upon a what stage it is detected. In many cases, it may be detected incidentally while doing basic scans like ultrasound and CT scans, it may be totally non symptomatic in its early stage. Symptoms mostly come in the late stage of the disease when liver functioning is impacted. Important symptoms include the derrangement in the liver function which can be detected in the form of Jaundice.This very commonly seen with Yellowish discoloration of the eyes, skin or urine. When liver cancer is large in size, it can have pressure effects which can cause pain in the upper abdomen, can impair the metabolism of the liver and can lead to abnormal distinction of the stomach with fluid in the Peritoneal cavity which is seen as asicitis. Other important symptoms can be loss of appetite, difficulty in digestion of the foods and continues loss of the weight.
Liver Cancer Causes
Liver Cancer is abnormal division of the liver cells which is not under any control mechanism and thus uncontrolled division of the cells lead to excessive formation of the liver tumor cells. There are no specific causes of the liver tumor however, it is associated with Multiple factors Which lead to the cirrhosis in the liver. Various diseases which can cause cirrhosis of liver, include excessive fatty liver, excessive uncontrolled intake of the alcohol and viral infections like Hepatitis b and hepatitis c. Liver has a potential to repair itself. However due to defect in this control mechanism there is uncontrolled division of the liver cells which turn into the cancer cells and can cause liver cancer.
Treatmentas of Liver Cancer
Multiple treatments have developed over period of time for the treatment of the liver cancer which includes conventional treatments like surgical resection of the tumor to more advanced treatmeants like microwave ablation of the tumor.
Cancer has been conventionally treated through ayurvedic treatments and naturopathy,however with limited success rate. Surgical treatment involved complete removal of a section of the liver or a lobe of liver, where the cancer is present. However, it is in the expensive treatment which requires long stay in the hospital. And is highly expensive and cannot be carried out in every patient due to limitations. Other treatments that have developed our like liver transplantation. However, it is very expensive and and is very limitedly carried out due to non availability of the donor in many cases.
Radiotherapy and intravenous chemotherapy:
Radiotherapy and conventional intravenous chemotherapy have provided limited success rate in the treatment of the liver cancer.
More recently, advanced form of three tretments have developed In the recent times which not only prevents excessive stay in the hospital and is highly affordable.
Microwave ablation:
Microwave ablation is a new form of treatment which has many advantages in the form of limited hospital stay, no major cut and sutures and is highly affordable. It is a procedure which can be carried out on daycare basis also, and involve heat supply to the cancer cells through a specific electrode or antenna to kill the cancer cells. It can completely cure the liver cancer where the size of the tumor is less than 5 cm and upto 3 nodules. However recent advancement allows treatment upto 5 nodules in many cases with success.
Trans arterial chemoembolisation(Tace):
Trans arterial chemoembolisation(Tace) Is a palliative form of treatment which desires to control the disease where it cannot be completely finished. However it has good effect in prolongation the life of the patient. The procedure works in 2 ways. It's not only supplies the chemo therapeutic drug to the tumor through the blood vessels at the site of the tumor rather than to the whole body and thus producing high impact in killing the tumor cells. Simultaneously it also blocks the blood supply of the tumor and thus helps in doubling the effect of the treatment. It is carried by the highly specialized group of doctors called intervention radiologist who performe this procedure under the fluoroscopic guidance. It has limited complications like post procedure Pain and depletion in the normal functioning liver cells. However, it can be very well managed through the supportive medications.Both Tace and microwave ablation can be used alone or in combination to successfully treat the tumor.
TARE:
TARE is another advanced form of treatment which requires radioactive material to kill the tumor cells. It is mostly carried in advanced liver cancer to control the disease.
Treatment Success Rate
The success rate of all the treatments depend on the stage at which the disease is detected. Earlier the disease is detected high is the success rates. Mostly if the disease is localized and it's small in size, it can be carried out in a curative intent through the treatments like liver resection and microwave ablation and many cases of the Liver tumor have been successfully treated through this treatment over the period of time.
Other procedures like TACE and TARE have palliative intent In controlling the disease rather than completely curing the disease however In combination with the other procedures, they can have curative impact also.
Cost:
Cost Of the disease treatment depends upon what treatment is taken.
Liver resection and liver transplant are highly expensive treatments and cannot be carried out in all patients. Microwave ablation and Tace are cost effective treatment and can be done in less than one-fifth the cost of liver transplant and can produce complete cure of the disease and are highly effective.
Best Liver Cancer Treatment Hospitals
Liver cancer treatment requires complex approach Which is supported by multiple group of doctors like intervention radiologist, gastro-physicians and oncologist. Treatment is mostly done in hospitals where all this group of doctors are available.
Intervention radiologists are a highly Expert group of doctors, who helps in treatment of the disease in minimally invasive manner.
IRfacilities is group of intervention Radiologist, who are highly skilled in treatment of liver cancer. They have treated more than 1000 cases of the liver tumor and not only provides treatment, pre treatment Counseling and also post treatment support together with the treatment itself. They are highly expert group of doctors in in their field who deal with the cases, both from domestic and international arena and have highly successfully cured many cases Of the liver cancer.
Prevention and Early Treatment
Prevention of the liver cancer can be done in preventing the associated agents. Viral infections are important causes that have been associated with the liver cancer and does vaccination for hepatitis b viruses can be helpful. Early tretment of hepatits c should be done with regular monitoring using the ultrasound and ct scan to detect the cancer at early stage.
Early tretment of fatty liver is important. With all the medical aspects good healthy life style should be followed with regular excercise and prevention of alcohal intake.
Leading Core
Our Team
Leading Team of Core Neuroradiologists & Interventional Radiologists of the Region.
Dr. SANDEEP SHARMA
(MD, DM Neuro Radiology AIIMS)
Dr. LOKESH SINGH
(Ex. AIIMS, PGIMER)
Dr. GAURAV DHAWAN
(Ex. TMH, SGRH)
Dr. JASPREET SINGH
(Ex. SSCHRC Bangalore)